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Pathology

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pawsPathologyManual: Alpha-Fetoprotein, Amniotic Fluid

Lonic Code

 

Test Name

Alpha-Fetoprotein, Amniotic Fluid

Synonyms

AFP-AF, Alpha-Fetoprotein Amniotic Fluid

Test Consists

If AFP is positive, then acetylcholinesterase will be performed at an additional charge.

Specimen Requirements

1.0 mL amniotic fluid

Volume and Container

Sterile container

Storage and Transport

Amniotic fluid stored refrigerated until ready for transport to Mayo Medical Laboratory Rochester

Critical Values

 

Causes for Rejection

Specimens other than amniotic fluid

Turn Around Time

5-15 business days from time of collection

Availability

Monday-Friday from 8 am-5 pm, except observed holidays

CPT / HCPCS Code

82106, 82013 (if appropriate)

Medicare Fee

 

Comments

 

Row Stamp

38,838,597

Last Updated

 

Volume

 

Minimum Volume

 

Indications

Screening test to detect open neural tube defects or other fetal abnormalities.  Follow-up testing for patients with elevated serum AFP or in conjunction with cytogenetic testing.

Professional Fee

 

Tech Charge

 

Total Fee

 

Special Instructions

 

Lab

Mayo Medical Laboratory Rochester

Schedule

Test performed Monday-Friday and Saturday at Mayo Medical Laboratory Rochester

Request Form

MayoConnect Additional Test Information Form and Cytogenetics/AFP Congenital Disorders Request Form.  Required information include: Date ultrasound performed, gestational dating on the day of ultrasound, collection date. 

Methodology

Immunoenzymatic Assay, Polyacrylamide Electrophoresis

Patient Prep

 

Post Processing

 

Collection Guidelines

 

Reference Range

See reference lab report

Limitations and Contraindications

This test is to be used for screening only.

Interpretation

A diagnostic AFP cutoff level of 2.0 MoM, followed by AChE confirmatory testing on positive results, is capable of detecting 96% of open spina bifida cases with a false-positive rate of only 0.06% in non blood-stained specimens.

Additional Information

Gestational age must be between 13-24 weeks; 16-18 weeks preferred.

CPOE Test Name

Ref Misc Referral Lab Test, type AFP AF in Test Name REF

Status

1

AUDIT_DEL

 

Attachments

Created at 9/8/2014 5:57 PM by Bradshaw, Keir
Last modified at 9/8/2014 5:57 PM by Bradshaw, Keir