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Lonic Code

 

Test Name

ANCA

Synonyms

cANCA/pANCA, Autoimmune Vasculitis, ANCA

Test Consists

Values for Myeloperoxidase (MPO) antibody and Proteinase 3 antibody (PR3); if either is >=0.4 U, then cytoplasmic neutrophilic antibodies will be performed at an additional charge.

Specimen Requirements

2.0 mL blood

Volume and Container

5.0 mL gold top SST blood tube

Storage and Transport

Serum stored refrigerated until ready for transport to Mayo Medical Laboratory Rochester

Critical Values

 

Causes for Rejection

Specimens other than serum, gross hemolysis, lipemia, icteric, warm serum

Turn Around Time

3-8 business days from time of collection

Availability

Monday-Friday from 8 am-5 pm, except observed holidays

CPT / HCPCS Code

83516x2, 86255, 86256 (if appropriate)

Medicare Fee

 

Comments

 

Row Stamp

38,869,124

Last Updated

 

Volume

 

Minimum Volume

 

Indications

Evaluating patients suspected of having autoimmune vasculitis, both Wegener's granulomatosis and microscopic polyangiitis

Professional Fee

 

Tech Charge

 

Total Fee

 

Special Instructions

 

Lab

Mayo Medical Laboratory Rochester

Schedule

Test performed Monday-Saturday at Mayo Medical Laboratory Rochester

Request Form

 

Methodology

Multiplex flow immunoassay, Indirect immunofluorescence (if appropriate)

Patient Prep

 

Post Processing

 

Collection Guidelines

 

Reference Range

See reference lab report

Limitations and Contraindications

 

Interpretation

Positive results PR3 ANCA and cANCA or pANCA are consistent with the diagnosis of WG, either systemic WG with respiratory and renal involvement or limited WG with more restricted end-organ involvement.  Positive results for MPO ANCA and pANCA are consistent with the diagnosis of autoimmune vasculitis including MPA or pauci-immune necrotizing glomerulonephritis.

Additional Information

 

CPOE Test Name

Ref ANCAP, Ref ANCA Vasculitis

Status

1

AUDIT_DEL

 

Attachments

Created at 9/8/2014 5:57 PM by Bradshaw, Keir
Last modified at 9/8/2014 5:57 PM by Bradshaw, Keir