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Point of Care Testing
Pathology Lab Manual
All Site Content
Quad Prenatal Screen, AFP4 Screening
AFP, hCG, uE3, dimeric Inhibin-A
5.0 mL blood
Volume and Container
5.0 mL gold top SST blood tube
Storage and Transport
Serum stored refrigerated until ready for transport to Genzyme Genetic Laboratory
Causes for Rejection
Specimens other than serum, warm serum
Turn Around Time
3-8 business days from time of collection
Monday-Friday from 8 am-5 pm, except observed holidays
CPT / HCPCS Code
82105, 82677, 84702, 86336
Screening for fetal Down syndrome, trisomy 18, and open neural tube defects between 15-21 weeks, optimal time being between 16-18 weeks
Genzyme Genetic Laboratory
Completed Genzyme Genetic AFP4 requisition
See reference lab report
Limitations and Contraindications
The four biochemical markers are analyzed to provide risk assessments for fetal Down syndrome, trisomy 18, and open neural tube defects
CPOE Test Name
Ref Quad Screen, Ref Quad
Created at 9/8/2014 5:57 PM by Bradshaw, Keir
Last modified at 9/8/2014 5:57 PM by Bradshaw, Keir
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