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Pathology

:

pawsPathologyManual: Alpha-1-Antitrypsin

Lonic Code

 

Test Name

Alpha-1-Antitrypsin

Synonyms

A1A, Antitrypsin Alpha, Alpha-1-Antitrypsin

Test Consists

 

Specimen Requirements

2.0 mL blood

Volume and Container

5.0 mL gold top SST blood tube

Storage and Transport

Serum stored refrigerated until ready for transport to Mayo Medical Laboratory Rochester

Critical Values

 

Causes for Rejection

Specimen other than serum, gross lipemia

Turn Around Time

3-10 business days from time of collection

Availability

Monday-Friday from 8 am-5 pm, except observed holidays

CPT / HCPCS Code

82103

Medicare Fee

 

Comments

 

Row Stamp

38,839,295

Last Updated

 

Volume

 

Minimum Volume

 

Indications

Diagnosis of A1A deficiency.  Work-up of individuals with suspected disorders such as familial chronic obstructive lung disease.

Professional Fee

 

Tech Charge

 

Total Fee

 

Special Instructions

 

Lab

Mayo Medical Laboratory Rochester

Schedule

Test performed Monday-Saturday at Mayo Medical Laboratory Rochester

Request Form

 

Methodology

Nephelometry

Patient Prep

 

Post Processing

 

Collection Guidelines

 

Reference Range

See reference lab report

Limitations and Contraindications

Low A1A levels may result from liver disease, and Genotyping should be done to confirm A1A deficiency disease.  A1A is an acute-phase reactant and any inflammatory process will elevate serum A1A levels.

Interpretation

Patients with <70 mg/dL may have a homozygous deficiency and are at risk for early lung disease.

Additional Information

 

CPOE Test Name

Ref A1-Antitrypsin, Ref A1AT

Status

1

AUDIT_DEL

 

Attachments

Created at 9/8/2014 5:56 PM by Bradshaw, Keir
Last modified at 9/8/2014 5:56 PM by Bradshaw, Keir